TCF-1 at the Tfh and Th1 Divergence

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Abstract

Three recent studies provide new insight into the mechanisms that promote the differentiation of antigen-primed T cells into the follicular helper T (Tfh) lineage, revealing a key role for the transcription factor TCF-1 in the regulation of the Bcl6-Blimp-1 axis that mediates the divergence between the Tfh and the Th1 lineages. ? 2015 Elsevier Ltd.
Original languageEnglish
Pages (from-to)758-760
Number of pages3
JournalTrends in Immunology
Volume36
Issue number12
DOIs
Publication statusPublished - 2015

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