Tasteless Food Reward

Zane Bruce Andrews, Tamas L Horvath

Research output: Contribution to journalLetterOther

6 Citations (Scopus)


Food palatability acts on the dopaminergic reward system to override homeostatic control; however, whether postingestive calorie load in the absence of taste affects this system remains unclear. In this issue of Neuron, de Araujo et al. show that mice lacking functional sweet taste receptors (trpm5-/-) develop a preference for sucrose by activating the mesolimbic dopamine-accumbal pathway, solely based on calorie load.
Original languageEnglish
Pages (from-to)806 - 808
Number of pages3
Issue number6
Publication statusPublished - 2008

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