Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

Aleksandra Muratovska; Robert N Lightowlers; Robert W Taylor; Douglass M Turnbull; Robin AJ Smith; Jacqueline Anne Wilce; Stephen W Martin; Michael P Murphy

doi:10.1093/nar/29.9.1852

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

Aleksandra Muratovska
, Robert N Lightowlers
, Robert W Taylor
, Douglass M Turnbull
, Robin AJ Smith
, Jacqueline Anne Wilce
, Stephen W Martin
, Michael P Murphy

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

161 Citations (Scopus)

Original language	English
Pages (from-to)	1852 - 1863
Number of pages	12
Journal	Nucleic Acids Research
Volume	29
Issue number	9
DOIs	https://doi.org/10.1093/nar/29.9.1852
Publication status	Published - 2001

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10.1093/nar/29.9.1852

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Muratovska, A., Lightowlers, R. N., Taylor, R. W., Turnbull, D. M., Smith, R. AJ., Wilce, J. A., Martin, S. W., & Murphy, M. P. (2001). Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease. Nucleic Acids Research, 29(9), 1852 - 1863. https://doi.org/10.1093/nar/29.9.1852

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author = "Aleksandra Muratovska and Lightowlers, \{Robert N\} and Taylor, \{Robert W\} and Turnbull, \{Douglass M\} and Smith, \{Robin AJ\} and Wilce, \{Jacqueline Anne\} and Martin, \{Stephen W\} and Murphy, \{Michael P\}",

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Muratovska, A, Lightowlers, RN, Taylor, RW, Turnbull, DM, Smith, RAJ, Wilce, JA, Martin, SW & Murphy, MP 2001, 'Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease', Nucleic Acids Research, vol. 29, no. 9, pp. 1852 - 1863. https://doi.org/10.1093/nar/29.9.1852

Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease. / Muratovska, Aleksandra; Lightowlers, Robert N; Taylor, Robert W et al.
In: Nucleic Acids Research, Vol. 29, No. 9, 2001, p. 1852 - 1863.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease

AU - Muratovska, Aleksandra

AU - Lightowlers, Robert N

AU - Taylor, Robert W

AU - Turnbull, Douglass M

AU - Smith, Robin AJ

AU - Wilce, Jacqueline Anne

AU - Martin, Stephen W

AU - Murphy, Michael P

PY - 2001

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DO - 10.1093/nar/29.9.1852

M3 - Article

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VL - 29

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EP - 1863

JO - Nucleic Acids Research

JF - Nucleic Acids Research

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