TY - JOUR
T1 - Takotsubo cardiomyopathy
T2 - Reversible elevation in microcirculatory resistance
AU - Layland, Jamie
AU - Whitbourn, Robert
AU - MacIsaac, Andrew
AU - Somaratne, Jithendra
AU - Wilson, Andrew
PY - 2012/1/1
Y1 - 2012/1/1
N2 - We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.
AB - We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.
KW - Cardiomyopathy
KW - Microcirculation
KW - Takotsubo
UR - http://www.scopus.com/inward/record.url?scp=84856050452&partnerID=8YFLogxK
U2 - 10.1016/j.carrev.2011.06.005
DO - 10.1016/j.carrev.2011.06.005
M3 - Article
C2 - 21856251
AN - SCOPUS:84856050452
SN - 1553-8389
VL - 13
SP - 66
EP - 68
JO - Cardiovascular Revascularization Medicine
JF - Cardiovascular Revascularization Medicine
IS - 1
ER -