Takotsubo cardiomyopathy: Reversible elevation in microcirculatory resistance

Jamie Layland, Robert Whitbourn, Andrew MacIsaac, Jithendra Somaratne, Andrew Wilson

Research output: Contribution to journalArticleOtherpeer-review

6 Citations (Scopus)


We present a case of takotsubo cardiomyopathy and demonstrate an initial elevation of microcirculatory resistance (IMR) that reduced on follow-up evaluation. This corresponded with improvements in left ventricular function. We postulate that the changes in microvascular resistance reflect favourable left ventricular microvascular remodelling. The measurement of IMR, a novel marker of microcirculatory dysfunction, provides novel insights into the pathophysiology of this condition.

Original languageEnglish
Pages (from-to)66-68
Number of pages3
JournalCardiovascular Revascularization Medicine
Issue number1
Publication statusPublished - 1 Jan 2012
Externally publishedYes


  • Cardiomyopathy
  • Microcirculation
  • Takotsubo

Cite this