Tailoring substrate hydrophilicity using grafted polypeptide nanocoatings

Steven Harris Wibowo, Adrian Sulistio, Edgar Hoe Hon Wong, Anton Blencowe, Greg Qiao

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9 Citations (Scopus)


Peptide nanocoatings with tailored surface-wetting properties were formed on a range of organic (cellulose and cotton) and inorganic (glass) substrates via surface-initiated ring-opening polymerization of amino acid N-carboxyanhydride derivatives. The film thickness, surface roughness, and wettability can be tuned by controlling the polymerization time and the type of N-carboxyanhydride derivative used (i.e. lysine or valine). Whereas poly(l-lysine) coatings are hydrophilic, poly(l-valine) coatings exhibit water-repellent properties. The functional polypeptide nanocoatings can potentially be applied to waterproof woven fabrics, macromolecular separation technologies, biodiagnostic sensors, and sustained drug-release wound dressings.

Original languageEnglish
Pages (from-to)598-602
Number of pages5
JournalAustralian Journal of Chemistry
Issue number4
Publication statusPublished - 2014
Externally publishedYes

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