T Cell LEGO: Identifying the Master Builders and What They Do

Jasmine Li; Stephen J. Turner

doi:10.1016/j.immuni.2018.02.004

T Cell LEGO: Identifying the Master Builders and What They Do

Jasmine Li, Stephen J. Turner

Research output: Contribution to journal › Editorial › Other › peer-review

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Abstract

Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development. Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.

Original language	English
Pages (from-to)	185-187
Number of pages	3
Journal	Immunity
Volume	48
Issue number	2
DOIs	https://doi.org/10.1016/j.immuni.2018.02.004
Publication status	Published - 20 Feb 2018

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title = "T Cell LEGO: Identifying the Master Builders and What They Do",

abstract = "Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development. Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.",

author = "Jasmine Li and Turner, {Stephen J.}",

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AU - Turner, Stephen J.

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N2 - Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development. Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.

AB - Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development. Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.

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DO - 10.1016/j.immuni.2018.02.004

M3 - Editorial

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SN - 1074-7613

VL - 48

SP - 185

EP - 187

JO - Immunity

JF - Immunity

IS - 2

ER -

T Cell LEGO: Identifying the Master Builders and What They Do

Abstract

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