T Cell LEGO: Identifying the Master Builders and What They Do

Research output: Contribution to journalEditorialOtherpeer-review

Abstract

Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development. Understanding how cell fate decisions are made during cellular differentiation and the mechanisms that drive them is a holy grail of cell biology. In this issue of Immunity, Hu et al. (2018) and Johnson et al. (2018) demonstrate that key transcriptional regulators and global changes in nuclear architecture underlie differentiation decisions during T cell development.

Original languageEnglish
Pages (from-to)185-187
Number of pages3
JournalImmunity
Volume48
Issue number2
DOIs
Publication statusPublished - 20 Feb 2018

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