Systemic arterial stiffness in infants with bronchopulmonary dysplasia: Potential cause of systemic hypertension

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Objective: Systemic hypertension is common among preterm infants with severe bronchopulmonary dysplasia (BPD); the exact cause is unknown. The objective of this preliminary hypothesis generating study was to examine systemic arterial structure and vasomotor function in a cohort of preterm infants with severe BPD, using a cohort of preterm infants without BPD and a cohort of term infants for comparison. Study Design: After obtaining informed consent, we measured aortic wall thickness and vasomotor function by ultrasonography in 20 infants with severe BPD, 7 infants with no BPD, and compared them with 20 healthy term infants. Results: Maximum aortic thickness was significantly higher in infants with BPD (827±163 μm) compared to those with no BPD (674±22 μm) and term infants (657±67 μm) (unadjusted P

Original languageEnglish
Pages (from-to)564-569
Number of pages6
JournalJournal of Perinatology
Volume36
Issue number7
DOIs
Publication statusPublished - 1 Jul 2016

Cite this

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abstract = "Objective: Systemic hypertension is common among preterm infants with severe bronchopulmonary dysplasia (BPD); the exact cause is unknown. The objective of this preliminary hypothesis generating study was to examine systemic arterial structure and vasomotor function in a cohort of preterm infants with severe BPD, using a cohort of preterm infants without BPD and a cohort of term infants for comparison. Study Design: After obtaining informed consent, we measured aortic wall thickness and vasomotor function by ultrasonography in 20 infants with severe BPD, 7 infants with no BPD, and compared them with 20 healthy term infants. Results: Maximum aortic thickness was significantly higher in infants with BPD (827±163 μm) compared to those with no BPD (674±22 μm) and term infants (657±67 μm) (unadjusted P",
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Systemic arterial stiffness in infants with bronchopulmonary dysplasia : Potential cause of systemic hypertension. / Sehgal, A.; Malikiwi, A.; Paul, E.; Tan, Kenneth; Menahem, S.

In: Journal of Perinatology, Vol. 36, No. 7, 01.07.2016, p. 564-569.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Tan, Kenneth

AU - Menahem, S.

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