We demonstrate an efficient synthesis of novel layered double hydroxide mesoporous silica core–shell nanostructures (LDH@mSiO2) that have a hexagonal MgAl-LDH nanoplate core and an ordered mesoporous silica shell with perpendicularly oriented channels via a surfactant-templating method. Transmission electron microscopy, X-ray diffraction and N2 sorption analyses confirmed that the obtained nanostructures have uniform accessible mesopores (∼2.2 nm), high surface area (∼430 m2 g−1), and large pore volume (∼0.22 cm3 g−1). Investigations of drug release and bio-imaging showed that this material has a slow release effect of ibuprofen and good biocompatibility. This work provides an economical approach to fabricate LDH@mSiO2 core–shell nanostructures, which may have great potential in broad drug delivery and hyperthermia therapy applications.
|Pages (from-to)||4069 - 4073|
|Number of pages||5|
|Publication status||Published - 2011|
Centre for Electron Microscopy (MCEM)
Flame Sorrell (Manager) & Peter Miller (Manager)Office of the Vice-Provost (Research and Research Infrastructure)