Synthesis of various glycopolymer architectures via RAFT polymerization: From block copolymers to stars

Julien Bernard, Xiaojuan Hao, Thomas P. Davis, Christopher Barner-Kowollik, Martina H. Stenzel

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153 Citations (Scopus)


Well-defined linear poly(acryloyl glucosamine) (PAGA) exhibiting molar masses ranging from 3 to 120 K and low polydispersities have been prepared via reversible addition-fragmentation chain transfer polymerization (RAFT) in aqueous solution without recourse to protecting group chemistry. The livingness of the process was further demonstrated by successfully chain-extending one of these polymers with N-isopropylacrylamide affording narrow dispersed thermosensitive diblocks. This strategy of polymerization was finally extended to the preparation of glycopolymer stars from Z designed non-water-soluble trifunctional RAFT agent. After the growth of very short blocks of poly(hydroxyethyl acrylate) (DPnbranch = 10), AGA was polymerized in aqueous solution in a controlled manner affording well-defined 3-arm glycopolymer stars.

Original languageEnglish
Pages (from-to)232-238
Number of pages7
Issue number1
Publication statusPublished - 1 Jan 2006
Externally publishedYes

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