@article{8c7826313b2c4f119b23a14f8bf670e1,
title = "Synthesis of the C50 diastereomers of the C33-C51 fragment of stambomycin D",
abstract = "As products of genome mining, the stereochemical assignment of the macrolide antibiotics stambomycins A-D has been made on the basis of sequence analysis of the associated polyketide synthase, aside from two stereocentres at C28 and C50. Here we describe syntheses of the two C50 diastereomers of the C33-C51 region of the stambomycins, which support the PKS-based configurational assignment, and establish a strategy suitable for access to the extended stambomycin framework. ",
author = "Yongchen Wang and Venkaiah Chintalapudi and Gudmundsson, {Haraldur G.} and Challis, {Gregory L.} and Anderson, {Edward A.}",
note = "Funding Information: We thank the Marie Sk{\l}odowska-Curie actions for an Individual Fellowship (V. C., GA No. 702385), and the Leverhulme Trust for funding (H. G. G., RPG-2015-003). E. A. A. thanks the EPSRC for additional support (EP/ S013172/1). Dr Lijiang Song (University of Warwick) is thanked for re-examining the original stambomycin HSQC data. Publisher Copyright: {\textcopyright} the Partner Organisations.",
year = "2022",
month = jan,
day = "21",
doi = "10.1039/d1qo01635k",
language = "English",
volume = "9",
pages = "445--449",
journal = "Organic Chemistry Frontiers",
issn = "2052-4129",
publisher = "The Royal Society of Chemistry",
number = "2",
}