Sulforaphane (SFN) a naturally occurring isothiocyanate present in broccoli, shows strong evidence of anti-carcinogenic activity. The mechanism of action, absorption, distribution, metabolism and excretion of the compound is however still poorly understood and requires a radiolabelled version of the compound for further studies. The paper describes an optimised cold synthesis of SFN and a radiosynthesis of 14C-labelled SFN.
|Number of pages||8|
|Journal||Journal of Labelled Compounds and Radiopharmaceuticals|
|Publication status||Published - 12 May 2001|
- Anti-cancer compounds