Synthesis of 14C-labelled sulforaphane

Nikolai Kuhnert, Birgit Holst, Gary Williamson

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17 Citations (Scopus)


Sulforaphane (SFN) a naturally occurring isothiocyanate present in broccoli, shows strong evidence of anti-carcinogenic activity. The mechanism of action, absorption, distribution, metabolism and excretion of the compound is however still poorly understood and requires a radiolabelled version of the compound for further studies. The paper describes an optimised cold synthesis of SFN and a radiosynthesis of 14C-labelled SFN.

Original languageEnglish
Pages (from-to)347-354
Number of pages8
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Issue number5
Publication statusPublished - 12 May 2001
Externally publishedYes


  • C-labelling
  • Anti-cancer compounds
  • Isothiocyanates
  • Phytochemicals

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