Synthesis of Sub-100 nm Glycosylated Nanoparticles via a One Step, Free Radical, and Surfactant Free Emulsion Polymerization

Andrew M. Lunn; Sébastien Perrier

doi:10.1002/marc.201800122

Synthesis of Sub-100 nm Glycosylated Nanoparticles via a One Step, Free Radical, and Surfactant Free Emulsion Polymerization

Andrew M. Lunn, Sébastien Perrier

Drug Delivery Disposition & Dynamics

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

The facile synthesis of sub-100 nm glyco nanoparticles is presented via a one-step, free radical, and surfactant free emulsion polymerization. It is shown that by using sterically large, hydrophilic glycomonomers such as a lactose acrylamide with the charged azo initiator 4,4'-azobis(4-cyanovaleric acid), growing particles are stabilized enough to reproducibly produce well defined (PDi ≤ 0.1) glycoparticles with diameters below 100 nm.

Original language	English
Article number	1800122
Number of pages	5
Journal	Macromolecular Rapid Communications
Volume	39
Issue number	19
DOIs	https://doi.org/10.1002/marc.201800122
Publication status	Published - 2018

Keywords

Emulsion polymerization
Glyco-nanoparticles
Surfactant free

Access to Document

10.1002/marc.201800122

Link to publication in Scopus

Cite this

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abstract = "The facile synthesis of sub-100 nm glyco nanoparticles is presented via a one-step, free radical, and surfactant free emulsion polymerization. It is shown that by using sterically large, hydrophilic glycomonomers such as a lactose acrylamide with the charged azo initiator 4,4'-azobis(4-cyanovaleric acid), growing particles are stabilized enough to reproducibly produce well defined (PDi ≤ 0.1) glycoparticles with diameters below 100 nm.",

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