Synthesis of silica-polymer core-shell nanoparticles by reversible addition-fragmentation chain transfer polymerization

John Moraes, Kohji Ohno, Thomas Maschmeyer, Sebastien Perrier

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)


Hybrid nanoparticles hold great promise for a range of applications such as drug-delivery vectors or colloidal crystal self-assemblies. The challenge of preparing highly monodisperse particles for these applications has recently been overcome by using living radical polymerization techniques. In particular, the use of reversible addition-fragmentation chain transfer (RAFT), initiated from silica surfaces, yields well-defined particles from a range of precursor monomers resulting in nanoparticles of tailored sizes that are accessible via the rational selection of polymerization conditions. Furthermore, using RAFT allows post-polymerization modification to afford multifunctional, monodisperse, nanostructures under mild and non-stringent reaction conditions. 

Original languageEnglish
Pages (from-to)9077-9088
Number of pages12
JournalChemical Communications
Issue number80
Publication statusPublished - 14 Oct 2013
Externally publishedYes

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