Synthesis of peptide-grafted comb polypeptides via polymerisation of NCA-peptides

Hiroshi Enomoto, Benjamin Nottelet, Soultan Al Halifa, Christine Enjalbal, Mathieu Dupré, Julien Tailhades, Jean Coudane, Gilles Subra, Jean Martinez, Muriel Amblard

Research output: Contribution to journalComment / DebateResearchpeer-review

8 Citations (Scopus)

Abstract

A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.
Original languageEnglish
Pages (from-to)409-411
Number of pages3
JournalChemical Communications
Volume49
Issue number4
DOIs
Publication statusPublished - 14 Jan 2013
Externally publishedYes

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