Synthesis of peptide-grafted comb polypeptides via polymerisation of NCA-peptides

Hiroshi Enomoto; Benjamin  Nottelet; Soultan Al Halifa; Christine Enjalbal; Mathieu Dupré; Julien Tailhades; Jean Coudane; Gilles Subra; Jean Martinez; Muriel Amblard

doi:10.1039/c2cc37597d

Synthesis of peptide-grafted comb polypeptides via polymerisation of NCA-peptides

Hiroshi Enomoto, Benjamin Nottelet, Soultan Al Halifa, Christine Enjalbal, Mathieu Dupré, Julien Tailhades, Jean Coudane, Gilles Subra, Jean Martinez, Muriel Amblard

Research output: Contribution to journal › Comment / Debate › Research › peer-review

11 Citations (Scopus)

Abstract

A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.

Original language	English
Pages (from-to)	409-411
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	4
DOIs	https://doi.org/10.1039/c2cc37597d
Publication status	Published - 14 Jan 2013
Externally published	Yes

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abstract = "A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology. ",

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AU - Enomoto, Hiroshi

AU - Nottelet, Benjamin

AU - Halifa, Soultan Al

AU - Enjalbal, Christine

AU - Dupré, Mathieu

AU - Tailhades, Julien

AU - Coudane, Jean

AU - Subra, Gilles

AU - Martinez, Jean

AU - Amblard, Muriel

PY - 2013/1/14

Y1 - 2013/1/14

N2 - A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.

AB - A straightforward synthesis of comb-polypeptides of repeated peptide sequences was developed. These polypeptides were obtained by ROP of defined NCA without any post-polymerization grafting. The key to this strategy relies on the preparation of pure NCA bearing a peptide sequence on its side chain, by an original solid supported methodology.

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DO - 10.1039/c2cc37597d

M3 - Comment / Debate

C2 - 23187977

AN - SCOPUS:84870944201

SN - 1359-7345

VL - 49

SP - 409

EP - 411

JO - Chemical Communications

JF - Chemical Communications

IS - 4

ER -

Synthesis of peptide-grafted comb polypeptides via polymerisation of NCA-peptides

Abstract

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