Synthesis of highly substituted indene derivatives by Bronsted acid catalyzed Friedel-Crafts reaction of homoallylic alcohols

Xiaoxiang Zhang, Wan Teng Teo, Weidong Rao, Dik-Lung Edmond Ma, Chung-Hang Duncan Leung, Philip Wai Hong Chan

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19 Citations (Scopus)


An efficient synthetic method to prepare highly substituted indenes in moderate to excellent yields that relies on Brønsted acid catalyzed Friedel–Crafts reaction of homoallylic alcohols under mild conditions is described.
Original languageEnglish
Pages (from-to)3881 - 3884
Number of pages4
JournalTetrahedron Letters
Issue number29
Publication statusPublished - 2014
Externally publishedYes


  • Indenes
  • indene derivatives
  • Cyclization

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