Synthesis of Heterocycles in Nonconventional Bio-based Reaction Media

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The reaction media typically constitute the largest part of the reaction mixture. In attempts to develop more sustainable methods for heterocyclic synthesis, bio-based reaction media are becoming a viable alternative replacing conventional fossil-derived organic solvents. A variety of bio-based media produced from renewable sources, often from biomass generated as waste by industries, allow the selection of a medium with specific properties satisfying reaction requirements. This chapter illustrates applications of several relatively more established bio-based media such as glycerol, lactic acid, ?-valerolactone, and 2-methyltetrahydrofuran and emerging bio-based solvents like Cyrene, limonene, eucalyptol, and p -cymene for the synthesis of heterocycles.

Original languageEnglish
Title of host publicationHeterocycles
Subtitle of host publicationSynthesis, Catalysis, Sustainability, and Characterization
EditorsTeresa M.V.D. Pinho e Melo, Marta Pineiro
Place of PublicationWeinheim Germany
PublisherWiley-VCH Verlag GmbH & Co. KGaA
Number of pages38
ISBN (Electronic)9783527832002, 9783527831999, 9783527832019
ISBN (Print)9783527348862
Publication statusPublished - 2022

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