TY - JOUR
T1 - Synthesis of 5,7-diamino1,2,4 triazolo[1,2-a1,3,5 triazines via annulation of 1,3,5-triazine ring onto 3(5)-amino-1,2,4-triazoles
AU - Dolzhenko, Anton V.
AU - Dolzhenko, Anna V.
AU - Chui, Wai Keung
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2007/2/1
Y1 - 2007/2/1
N2 - The 5,7-diamino[1,2,4]triazoeo[1,5-a][1,3,5]triazines were synthesized by cyclocondensation of 3(5)-amino-1,2,4-triazoles with cyanoguanidine. The substituted 3(5)-amino-1,2,4-triazoles were prepared from corresponding hydrazides and S-methylisothiourea via ring closure of the intermediate acylaminoguanidines. The 3,5-diamino-1,2,4-triazoles were prepared using partial aminolysis of dimethyl N-cyanodithiocarbonimidate followed by cyclization of the obtained N-substituted N′-cyano-S-methylisothioureas with hydrazine. The structures of the prepared compound were confirmed using NMR spectral data.
AB - The 5,7-diamino[1,2,4]triazoeo[1,5-a][1,3,5]triazines were synthesized by cyclocondensation of 3(5)-amino-1,2,4-triazoles with cyanoguanidine. The substituted 3(5)-amino-1,2,4-triazoles were prepared from corresponding hydrazides and S-methylisothiourea via ring closure of the intermediate acylaminoguanidines. The 3,5-diamino-1,2,4-triazoles were prepared using partial aminolysis of dimethyl N-cyanodithiocarbonimidate followed by cyclization of the obtained N-substituted N′-cyano-S-methylisothioureas with hydrazine. The structures of the prepared compound were confirmed using NMR spectral data.
UR - http://www.scopus.com/inward/record.url?scp=34250190191&partnerID=8YFLogxK
U2 - 10.3987/com-06-10936
DO - 10.3987/com-06-10936
M3 - Article
AN - SCOPUS:34250190191
SN - 0385-5414
VL - 71
SP - 429
EP - 436
JO - Heterocycles
JF - Heterocycles
IS - 2
ER -