Synthesis of 5-aminopyrazole-4-carbonitriles

Michael J. Dooley, Ronald J. Quinn, Peter J. Scammells

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Abstract

A one-pot reaction between substituted hydrazines, malononitrile and triethyl orthoformate leads directly to the formation of 1-substituted 5-aminopyrazole-4-carbonitriles. The scope and limitations of this synthetic procedure are discussed in relation to the well established synthesis of these compounds via substituted hydrazines and ethoxymethylenemalononitrile. © 1989 ASEG.
Original languageEnglish
Pages (from-to)747-750
Number of pages4
JournalAustralian Journal of Chemistry
Volume42
Issue number5
DOIs
Publication statusPublished - 1 Jan 1989

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