Synthesis of 3,5-dihydroxyphenylglycine derivatives and the C-terminal dipeptide of vancomycin

Martin J. Stone, Rachael A. Maplestone, Shirley K. Rahman, Dudney H. Williams

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22 Citations (Scopus)

Abstract

Syntheses of optically active 3,5-DMPG and racemic 3,5-DHPG, the latter suitably protected for incorporation into linear peptides modelled on vancomycin, are described and a synthesis of the optically pure protected C-terminal dipeptide of vancomycin is presented.

Original languageEnglish
Pages (from-to)2663-2666
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number23
DOIs
Publication statusPublished - 3 Jun 1991
Externally publishedYes

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