Synthesis of 2-substituted pyrazolo[3,4-d]pyrimidines

Graham Smith, Graham Smith, Graham Smith, Peter J. Scammells

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)


The reaction of 1-acetyl-2-phenylhydrazine with ethoxymethylenemalononitrile yielded [(4-cyano-1-phenylpyrazol-3-yl)aminomethylene]propanedinitrile. Hydrolysis followed by annulation with methyl isocyanate provided a synthetic route to 2-phenylpyrazolo[3,4-d]pyrimidines. © 1991 ASEG.
Original languageEnglish
Pages (from-to)1795-1801
Number of pages7
JournalAustralian Journal of Chemistry
Issue number12
Publication statusPublished - 1 Jan 1991

Cite this