Synthesis of 2-substituted pyrazolo[3,4-d]pyrimidines

Graham Smith, Graham Smith, Graham Smith, Peter J. Scammells

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Abstract

The reaction of 1-acetyl-2-phenylhydrazine with ethoxymethylenemalononitrile yielded [(4-cyano-1-phenylpyrazol-3-yl)aminomethylene]propanedinitrile. Hydrolysis followed by annulation with methyl isocyanate provided a synthetic route to 2-phenylpyrazolo[3,4-d]pyrimidines. © 1991 ASEG.
Original languageEnglish
Pages (from-to)1795-1801
Number of pages7
JournalAustralian Journal of Chemistry
Volume44
Issue number12
DOIs
Publication statusPublished - 1 Jan 1991

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