Synthesis of 2-substituted 3-acylbenzo[b]furans via the palladium catalysed carbonylative cyclisation of ortho-hydroxytolans

Henning Lütjens; Peter J. Scammells

doi:10.1055/s-1999-2764

Synthesis of 2-substituted 3-acylbenzo[b]furans via the palladium catalysed carbonylative cyclisation of ortho-hydroxytolans

Henning Lütjens, Peter J. Scammells

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

45 Citations (Scopus)

Abstract

A palladium-catalysed cyclisation with concomitant carbonylation via insertion of carbon monoxide was used to prepare several potential adenosine antagonists possessing a benzo[b]furan skeleton with a formyl group in the 3-position.

Original language	English
Pages (from-to)	1079-1081
Number of pages	3
Journal	Synlett
Issue number	7
DOIs	https://doi.org/10.1055/s-1999-2764
Publication status	Published - 1 Jan 1999

Keywords

Adenosine antagonist
Benzofuran
Carbonylative cyclisation
Palladium

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title = "Synthesis of 2-substituted 3-acylbenzo[b]furans via the palladium catalysed carbonylative cyclisation of ortho-hydroxytolans",

abstract = "A palladium-catalysed cyclisation with concomitant carbonylation via insertion of carbon monoxide was used to prepare several potential adenosine antagonists possessing a benzo[b]furan skeleton with a formyl group in the 3-position.",

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AU - Scammells, Peter J.

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AB - A palladium-catalysed cyclisation with concomitant carbonylation via insertion of carbon monoxide was used to prepare several potential adenosine antagonists possessing a benzo[b]furan skeleton with a formyl group in the 3-position.

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KW - Benzofuran

KW - Carbonylative cyclisation

KW - Palladium

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ER -

Synthesis of 2-substituted 3-acylbenzo[b]furans via the palladium catalysed carbonylative cyclisation of ortho-hydroxytolans

Abstract

Keywords

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