Synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes by cross-coupling induced by transition metals - formation of C-C bonds

Tomohiro Yasukawa, Katja S. Håheim, Janine Cossy

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Abstract

The synthesis of 1,3-disubstituted bicyclo[1.1.1]pentanes (BCPs), by forming a C-C bond, can be achieved by cross-coupling reactions using transition metal catalysts. Two main strategies are described to access these 1,3-disubstituted BCPs, either from nucleophilic BCPs or electrophilic BCPs. Mechanisms are included where relevant.

Original languageEnglish
Pages (from-to)7666-7680
Number of pages15
JournalOrganic & Biomolecular Chemistry
Volume21
Issue number38
DOIs
Publication statusPublished - 14 Oct 2023
Externally publishedYes

Cite this