Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 403 - 406 |
| Number of pages | 4 |
| Journal | MedChemComm |
| Volume | 6 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2015 |
Cite this
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Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents. / Manos-Turvey, Alexandra; Watson, Emma E; Sykes, Melissa L; Jones, Amy J; Baell, Jonathan Bayldon; Kaiser, Marcel; Avery, Vicky M; Payne, Richard James.
In: MedChemComm, Vol. 6, No. 3, 2015, p. 403 - 406.Research output: Contribution to journal › Article › Other › peer-review
TY - JOUR
T1 - Synthesis and evaluation of phenoxymethylbenzamide analogues as anti-trypanosomal agents
AU - Manos-Turvey, Alexandra
AU - Watson, Emma E
AU - Sykes, Melissa L
AU - Jones, Amy J
AU - Baell, Jonathan Bayldon
AU - Kaiser, Marcel
AU - Avery, Vicky M
AU - Payne, Richard James
PY - 2015
Y1 - 2015
N2 - The synthesis and anti-trypanosomal activity of a compound library based on a phenoxymethylbenzamide hit discovered in a high throughput screen is described. Several of the analogues exhibited potent activity against Trypanosoma brucei rhodesiense, a human infective strain of the trypanosome parasite, that serve as lead compounds for further optimisation.
AB - The synthesis and anti-trypanosomal activity of a compound library based on a phenoxymethylbenzamide hit discovered in a high throughput screen is described. Several of the analogues exhibited potent activity against Trypanosoma brucei rhodesiense, a human infective strain of the trypanosome parasite, that serve as lead compounds for further optimisation.
UR - http://pubs.rsc.org.ezproxy.lib.monash.edu.au/en/content/articlepdf/2015/md/c4md00406j
U2 - 10.1039/c4md00406j
DO - 10.1039/c4md00406j
M3 - Article
VL - 6
SP - 403
EP - 406
JO - MedChemComm
JF - MedChemComm
SN - 2040-2503
IS - 3
ER -