Abstract
The synthesis and anti-trypanosomal activity of a compound library based on a phenoxymethylbenzamide hit discovered in a high throughput screen is described. Several of the analogues exhibited potent activity against Trypanosoma brucei rhodesiense, a human infective strain of the trypanosome parasite, that serve as lead compounds for further optimisation.
Original language | English |
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Pages (from-to) | 403-406 |
Number of pages | 4 |
Journal | MedChemComm |
Volume | 6 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2015 |