Abstract
A putative antibacterial and antifungal compound, (R)-2-methylheptyl isonicotinate, was synthesized via reductive lactone alkylation of (R)-4-methyldihydrofuran-2(3H)-one. Structural characterisation data as well as bioassay results (with Bacillus subtilis or Escherichia coli) contradict those previously reported
Original language | English |
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Pages (from-to) | 5025-5027 |
Number of pages | 3 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 25 |
Issue number | 22 |
DOIs | |
Publication status | Published - 2015 |
Keywords
- Isonicotinate
- Total synthesis
- Antibacterial
- Natural product