Syntheses and effectiveness of functional peptide-based RAFT agents

Chao Chen, Fanxing Kong, Xiaohu Wei, San H. Thang

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Abstract

In this study, a series of functional peptide-based RAFT agents were designed and synthesized by the solid-phase supported peptide synthesis method. These novel RAFT agents have enabled chemists to make well-defined peptide-polymer conjugates with complicated topological structures. Additionally, our results have shown an unexpected reaction that takes place during these syntheses, and the conversion of a nitrile group to a carboxamide group has been evidently elucidated and unambiguously confirmed.

Original languageEnglish
Pages (from-to)10776-10779
Number of pages4
JournalChemical Communications
Volume53
Issue number78
DOIs
Publication statusPublished - 2017

Cite this