TY - JOUR
T1 - Symptoms, Sites, and Significance of Mycoplasma genitalium in Men Who Have Sex with Men
AU - Read, Tim R.H.
AU - Murray, Gerald L.
AU - Danielewski, Jennifer A.
AU - Fairley, Christopher K.
AU - Doyle, Michelle
AU - Worthington, Karen
AU - Su, Jenny
AU - Mokany, Elisa
AU - Tan, L. T.
AU - Lee, David
AU - Vodstrcil, Lenka A.
AU - Chow, Eric P.F.
AU - Garland, Suzanne M.
AU - Chen, Marcus Y.
AU - Bradshaw, Catriona S.
PY - 2019/4/1
Y1 - 2019/4/1
N2 - During 2016-2017, we tested asymptomatic men who have sex with men (MSM) in Melbourne, Australia, for Mycoplasma genitalium and macrolide resistance mutations in urine and anorectal swab specimens by using PCR. We compared M. genitalium detection rates for those asymptomatic men to those for MSM with proctitis and nongonococcal urethritis (NGU) over the same period. Of 1,001 asymptomatic MSM, 95 had M. genitalium; 84.2% were macrolide resistant, and 17% were co-infected with Neisseria gonorrhoeae or Chlamydia trachomatis. Rectal positivity for M. genitalium was 7.0% and urine positivity was 2.7%. M. genitalium was not more commonly detected in the rectums of MSM (n = 355, 5.6%) with symptoms of proctitis over the same period but was more commonly detected in MSM (n = 1,019, 8.1%) with NGU. M. genitalium is common and predominantly macrolide-resistant in asymptomatic MSM. M. genitalium is not associated with proctitis in this population.
AB - During 2016-2017, we tested asymptomatic men who have sex with men (MSM) in Melbourne, Australia, for Mycoplasma genitalium and macrolide resistance mutations in urine and anorectal swab specimens by using PCR. We compared M. genitalium detection rates for those asymptomatic men to those for MSM with proctitis and nongonococcal urethritis (NGU) over the same period. Of 1,001 asymptomatic MSM, 95 had M. genitalium; 84.2% were macrolide resistant, and 17% were co-infected with Neisseria gonorrhoeae or Chlamydia trachomatis. Rectal positivity for M. genitalium was 7.0% and urine positivity was 2.7%. M. genitalium was not more commonly detected in the rectums of MSM (n = 355, 5.6%) with symptoms of proctitis over the same period but was more commonly detected in MSM (n = 1,019, 8.1%) with NGU. M. genitalium is common and predominantly macrolide-resistant in asymptomatic MSM. M. genitalium is not associated with proctitis in this population.
KW - antibiotic resistance
KW - antimicrobial resistance
KW - Australia
KW - azithromycin
KW - bacteria
KW - men who have sex with men
KW - MSM
KW - Mycoplasma genitalium
KW - proctitis
KW - sexually transmitted infections
UR - http://www.scopus.com/inward/record.url?scp=85063254839&partnerID=8YFLogxK
U2 - 10.3201/eid2504.181258
DO - 10.3201/eid2504.181258
M3 - Article
C2 - 30882306
AN - SCOPUS:85063254839
SN - 1080-6040
VL - 25
SP - 719
EP - 727
JO - Emerging Infectious Diseases
JF - Emerging Infectious Diseases
IS - 4
ER -
