Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 89 - 95 |
| Number of pages | 7 |
| Journal | Journal of Affective Disorders |
| Volume | 162 |
| DOIs | |
| Publication status | Published - 2014 |
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Symptoms of depression and rates of neurocognitive impairment in HIV positive patients in Beijing, China. / Dwyer, Rosamond; Lu, Wenhui; Cysique, Lucette A; Brew, Bruce James; Lal, Luxshimi; Bain, Peter G; Wesselingh, Steven L; Wright, Edwina Jane.
In: Journal of Affective Disorders, Vol. 162, 2014, p. 89 - 95.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Symptoms of depression and rates of neurocognitive impairment in HIV positive patients in Beijing, China
AU - Dwyer, Rosamond
AU - Lu, Wenhui
AU - Cysique, Lucette A
AU - Brew, Bruce James
AU - Lal, Luxshimi
AU - Bain, Peter G
AU - Wesselingh, Steven L
AU - Wright, Edwina Jane
PY - 2014
Y1 - 2014
N2 - Background In China an estimated 780,000 people are living with HIV (PLWH). In high-income countries PLWH are at increased risk of depression, with subsequent adverse consequences for quality of life, and HIV-related morbidity and mortality. There are few data from low-and middle-income countries. The aims of this country-specific investigation of the Asia Pacific NeuroAIDS Consortium (APNAC) study were to establish the point prevalence, severity and HIV-related and non-HIV related correlates of depressive symptoms in PLWH, in Beijing, China. Method PLWH attending an outpatient clinic at Ditan Hospital, Beijing were recruited consecutively. Data sources were: study-specific questions about demographic characteristics, and health behaviours, the Centre for Epidemiological Studies Depression Scale (CES-D), the World Health Organisation Self-Reporting Questionnaire (SRQ-20) translated into Mandarin and administered as structured individual interviews, and a screen battery of four standard neuropsychological tests. Results In total 50/51 (98 ) eligible patients agreed to participate. Overall 28 scored CES-D=16 or SRQ20=10 and 18 in these clinical ranges on both measures; 69 were classified as being neuropsychologically impaired (scoring below 1 SD of the control value on at least two tests). Higher depressive symptom scores were associated with lower education, alcohol overuse and diminished motor ability (all p
AB - Background In China an estimated 780,000 people are living with HIV (PLWH). In high-income countries PLWH are at increased risk of depression, with subsequent adverse consequences for quality of life, and HIV-related morbidity and mortality. There are few data from low-and middle-income countries. The aims of this country-specific investigation of the Asia Pacific NeuroAIDS Consortium (APNAC) study were to establish the point prevalence, severity and HIV-related and non-HIV related correlates of depressive symptoms in PLWH, in Beijing, China. Method PLWH attending an outpatient clinic at Ditan Hospital, Beijing were recruited consecutively. Data sources were: study-specific questions about demographic characteristics, and health behaviours, the Centre for Epidemiological Studies Depression Scale (CES-D), the World Health Organisation Self-Reporting Questionnaire (SRQ-20) translated into Mandarin and administered as structured individual interviews, and a screen battery of four standard neuropsychological tests. Results In total 50/51 (98 ) eligible patients agreed to participate. Overall 28 scored CES-D=16 or SRQ20=10 and 18 in these clinical ranges on both measures; 69 were classified as being neuropsychologically impaired (scoring below 1 SD of the control value on at least two tests). Higher depressive symptom scores were associated with lower education, alcohol overuse and diminished motor ability (all p
UR - http://www.sciencedirect.com/science/article/pii/S0165032714001499#
U2 - 10.1016/j.jad.2014.03.038
DO - 10.1016/j.jad.2014.03.038
M3 - Article
VL - 162
SP - 89
EP - 95
JO - Journal of Affective Disorders
JF - Journal of Affective Disorders
SN - 0165-0327
ER -