Abstract
We report a case of steroid-and cyclophosphamide-resistant nephrotic syndrome secondary to minimal-change disease occurring in an otherwise healthy 19-year-old female, responding rapidly to two doses of rituximab therapy. Complete disease remission has been sustained up to last follow-up (32 months) despite CD19 recovery. Literature review suggests emerging evidence that rituximab may have a role to play in recurrent and/or refractory minimal-change disease.
Original language | English |
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Pages (from-to) | 293-295 |
Number of pages | 3 |
Journal | Clinical Kidney Journal |
Volume | 7 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
Keywords
- minimal-change disease
- nephrotic syndrome
- rituximab
- steroid resistance