Suspended core optical fibers for biological applications using UV wavelengths

Stephen C. Warren-Smith; G. Nie; J. Kobelke; R. Kostecki; L. A. Salamonsen; Tanya M Monro

doi:10.1117/12.970611

Suspended core optical fibers for biological applications using UV wavelengths

Stephen C. Warren-Smith, G. Nie, J. Kobelke, R. Kostecki, L. A. Salamonsen, Tanya M Monro

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

Abstract

We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspendedcore fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the standard enzyme activity assay of PC6, a biomarker of women's uterine fertility. Concentrations down to 500 nM have been measured using a 2.1 μm core diameter fiber.

Original language	English
Title of host publication	22nd International Conference on Optical Fiber Sensors
Volume	8421
DOIs	https://doi.org/10.1117/12.970611
Publication status	Published - 2012
Externally published	Yes
Event	International Conference on Optical Fiber Sensors 2012 - Beijing, China Duration: 15 Oct 2012 → 19 Oct 2012 Conference number: 22nd https://spie.org/Publications/Proceedings/Volume/8421 (Proceedings)

Conference

Conference	International Conference on Optical Fiber Sensors 2012
Abbreviated title	OFS 2012
Country/Territory	China
City	Beijing
Period	15/10/12 → 19/10/12
Internet address	https://spie.org/Publications/Proceedings/Volume/8421 (Proceedings)

Keywords

Biological sensing
Fertility
Fluorescence
Microstructured optical fibers

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10.1117/12.970611

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title = "Suspended core optical fibers for biological applications using UV wavelengths",

abstract = "We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspendedcore fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the standard enzyme activity assay of PC6, a biomarker of women's uterine fertility. Concentrations down to 500 nM have been measured using a 2.1 μm core diameter fiber.",

keywords = "Biological sensing, Fertility, Fluorescence, Microstructured optical fibers",

author = "Warren-Smith, {Stephen C.} and G. Nie and J. Kobelke and R. Kostecki and Salamonsen, {L. A.} and Monro, {Tanya M}",

year = "2012",

doi = "10.1117/12.970611",

language = "English",

isbn = "9780819491039",

volume = "8421",

booktitle = "22nd International Conference on Optical Fiber Sensors",

note = "International Conference on Optical Fiber Sensors 2012, OFS 2012 ; Conference date: 15-10-2012 Through 19-10-2012",

url = "https://spie.org/Publications/Proceedings/Volume/8421",

}

TY - GEN

T1 - Suspended core optical fibers for biological applications using UV wavelengths

AU - Warren-Smith, Stephen C.

AU - Nie, G.

AU - Kobelke, J.

AU - Kostecki, R.

AU - Salamonsen, L. A.

AU - Monro, Tanya M

N1 - Conference code: 22nd

PY - 2012

Y1 - 2012

N2 - We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspendedcore fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the standard enzyme activity assay of PC6, a biomarker of women's uterine fertility. Concentrations down to 500 nM have been measured using a 2.1 μm core diameter fiber.

AB - We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspendedcore fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the standard enzyme activity assay of PC6, a biomarker of women's uterine fertility. Concentrations down to 500 nM have been measured using a 2.1 μm core diameter fiber.

KW - Biological sensing

KW - Fertility

KW - Fluorescence

KW - Microstructured optical fibers

UR - http://www.scopus.com/inward/record.url?scp=84875609264&partnerID=8YFLogxK

U2 - 10.1117/12.970611

DO - 10.1117/12.970611

M3 - Conference Paper

AN - SCOPUS:84875609264

SN - 9780819491039

VL - 8421

BT - 22nd International Conference on Optical Fiber Sensors

T2 - International Conference on Optical Fiber Sensors 2012

Y2 - 15 October 2012 through 19 October 2012

ER -

Suspended core optical fibers for biological applications using UV wavelengths

Abstract

Conference

Keywords

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