Suspended core optical fibers for biological applications using UV wavelengths

Stephen C. Warren-Smith, G. Nie, J. Kobelke, R. Kostecki, L. A. Salamonsen, Tanya M Monro

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Abstract

We have demonstrated the use of suspended core optical fibers as dip sensors for biological applications based on fluorophores operating at UV wavelengths for the first time. In this paper, we have demonstrated the use of suspendedcore fibers to measure the fluorescence of 7-Amino-4-methylcoumarin (AMC), which is used as the transduction for the standard enzyme activity assay of PC6, a biomarker of women's uterine fertility. Concentrations down to 500 nM have been measured using a 2.1 μm core diameter fiber.

Original languageEnglish
Title of host publication22nd International Conference on Optical Fiber Sensors
Volume8421
DOIs
Publication statusPublished - 2012
Externally publishedYes
EventInternational Conference on Optical Fiber Sensors 2012 - Beijing, China
Duration: 15 Oct 201219 Oct 2012
Conference number: 22nd
https://spie.org/Publications/Proceedings/Volume/8421 (Proceedings)

Conference

ConferenceInternational Conference on Optical Fiber Sensors 2012
Abbreviated titleOFS 2012
CountryChina
CityBeijing
Period15/10/1219/10/12
Internet address

Keywords

  • Biological sensing
  • Fertility
  • Fluorescence
  • Microstructured optical fibers

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