Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation

Christopher John H Porter; Ann Marie Kaukonen; Benjamin James Boyd; Glenn A Edwards; William Neil Charman

doi:10.1023/B:PHAM.0000036914.22132.cc

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation

Christopher John H Porter
, Ann Marie Kaukonen
, Benjamin James Boyd
, Glenn A Edwards
, William Neil Charman

Drug Delivery Disposition & Dynamics

Research output: Contribution to journal › Article › Research › peer-review

244 Citations (Scopus)

Original language	English
Pages (from-to)	1405 - 1412
Number of pages	8
Journal	Pharmaceutical Research
Volume	21
Issue number	8
DOIs	https://doi.org/10.1023/B:PHAM.0000036914.22132.cc
Publication status	Published - 2004

Access to Document

10.1023/B:PHAM.0000036914.22132.cc

Cite this

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title = "Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation",

author = "Porter, \{Christopher John H\} and Kaukonen, \{Ann Marie\} and Boyd, \{Benjamin James\} and Edwards, \{Glenn A\} and Charman, \{William Neil\}",

year = "2004",

doi = "10.1023/B:PHAM.0000036914.22132.cc",

language = "English",

volume = "21",

pages = "1405 -- 1412",

journal = "Pharmaceutical Research",

issn = "0724-8741",

publisher = "Springer",

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}

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation. / Porter, Christopher John H; Kaukonen, Ann Marie; Boyd, Benjamin James et al.
In: Pharmaceutical Research, Vol. 21, No. 8, 2004, p. 1405 - 1412.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation

AU - Porter, Christopher John H

AU - Kaukonen, Ann Marie

AU - Boyd, Benjamin James

AU - Edwards, Glenn A

AU - Charman, William Neil

PY - 2004

Y1 - 2004

U2 - 10.1023/B:PHAM.0000036914.22132.cc

DO - 10.1023/B:PHAM.0000036914.22132.cc

M3 - Article

SN - 0724-8741

VL - 21

SP - 1405

EP - 1412

JO - Pharmaceutical Research

JF - Pharmaceutical Research

IS - 8

ER -