TY - JOUR
T1 - Survival analysis of patients with brain stroke in the presence of competing risks
T2 - A weibull parametric model
AU - Norouzi, Solmaz
AU - Fallah, Ramazan
AU - Pourdarvish, Ahmad
AU - Shamshirgaran, Seyed Morteza
AU - Farzipoor, Farshid
AU - Jafarabadi, Mohammad Asghari
N1 - Funding Information:
We want to thank the Research Deputy of Tabriz University of Medical Sciences for their appreciated contribution and support of this study (Grant no: 67813).
Publisher Copyright:
© 2021 Tehran University of Medical Sciences.
PY - 2021
Y1 - 2021
N2 - Introduction: This study aimed to assess the association between the survival of patients and outcomes in Brain Stroke (BS) in the presence of competing risks utilizing a Weibull parametric model. Methods: In this longitudinal study, 332 patients with BS were attended from Imam Khomeini Hospital in Ardabil, Iran. The stroke was diagnosed according to the medical history, current symptoms, and brain imaging during June 2008 and 2018. The survival of the patients, as the primary outcome, was modeled utilizing the best-chosen Weibull model in the presence of competing risks, including stroke and other factors (heart disease, blood pressure, etc.). Results: Older age at diagnosis (59-68 years: hazard ratio [HR]=2.27; 90% confidence interval [CI]: 1.65 to 3.12; 69-75 years: HR=4.79; 95% CI: 3.56 to 6.44; ≥76 years: HR, 4.92; 95% CI: 3.55 to 6.80), being a male (HR, 1.39; 95% CI: 1.11 to 1.75), being unemployed (HR, 1.44; 95% CI: 1.39 to 1.82), having heart disease (HR, 1.68; 95% CI: 1.38 to 2.06), and hemorrhagic stroke (HR, 2.21; 95% CI: 1.378to 2.75) were directly related to death from BS. Older age at diagnosis (59-68 years: HR, 18.01; 90% CI, 5.33 to 64.92; 75-69 years: HR, 18.56; 95% CI: 6.97 to 86.57; ≥76 years: HR, 28.90; 95% CI: 15.77 to 218.49), and urban residence (HR, 0.46; 90% CI, 0.28 to 0.77) were directly related to death from other causes. Conclusion: The recognition of the influential factors on the mortality of BS patients can allow increasing their survival.
AB - Introduction: This study aimed to assess the association between the survival of patients and outcomes in Brain Stroke (BS) in the presence of competing risks utilizing a Weibull parametric model. Methods: In this longitudinal study, 332 patients with BS were attended from Imam Khomeini Hospital in Ardabil, Iran. The stroke was diagnosed according to the medical history, current symptoms, and brain imaging during June 2008 and 2018. The survival of the patients, as the primary outcome, was modeled utilizing the best-chosen Weibull model in the presence of competing risks, including stroke and other factors (heart disease, blood pressure, etc.). Results: Older age at diagnosis (59-68 years: hazard ratio [HR]=2.27; 90% confidence interval [CI]: 1.65 to 3.12; 69-75 years: HR=4.79; 95% CI: 3.56 to 6.44; ≥76 years: HR, 4.92; 95% CI: 3.55 to 6.80), being a male (HR, 1.39; 95% CI: 1.11 to 1.75), being unemployed (HR, 1.44; 95% CI: 1.39 to 1.82), having heart disease (HR, 1.68; 95% CI: 1.38 to 2.06), and hemorrhagic stroke (HR, 2.21; 95% CI: 1.378to 2.75) were directly related to death from BS. Older age at diagnosis (59-68 years: HR, 18.01; 90% CI, 5.33 to 64.92; 75-69 years: HR, 18.56; 95% CI: 6.97 to 86.57; ≥76 years: HR, 28.90; 95% CI: 15.77 to 218.49), and urban residence (HR, 0.46; 90% CI, 0.28 to 0.77) were directly related to death from other causes. Conclusion: The recognition of the influential factors on the mortality of BS patients can allow increasing their survival.
KW - Competing risk
KW - Risk factors
KW - Stroke
KW - Survival analysis
KW - Weibull model
UR - http://www.scopus.com/inward/record.url?scp=85118183410&partnerID=8YFLogxK
U2 - 10.18502/jbe.v7i3.7295
DO - 10.18502/jbe.v7i3.7295
M3 - Article
AN - SCOPUS:85118183410
SN - 2383-4196
VL - 7
SP - 235
EP - 243
JO - Journal of Biostatistics and Epidemiology
JF - Journal of Biostatistics and Epidemiology
IS - 3
ER -
