Surgery for non-small cell lung cancer: systematic review and meta-analysis of randomised controlled trials

Gavin Wright, Renee L Manser, Graham Byrnes, David Hart, Donald Alexander Campbell

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    120 Citations (Scopus)

    Abstract

    Surgery is considered the treatment of choice for patients with resectable stage I and II (and some patients with stage IIIA)non-small cell lung cancer (NSCLC), but there have been no previously published systematic reviews. METHODS: A systematic review and meta-analysis of randomised controlled trials was conducted to determine whether surgical resection improves disease specific mortality in patients with stages I-IIIA NSCLC compared with non-surgical treatment, and to compare the efficacy of different surgical approaches. RESULTS: Eleven trials were included. No studies had untreated control groups.
    Original languageEnglish
    Pages (from-to)597 - 603
    Number of pages7
    JournalThorax
    Volume61
    Issue number7
    Publication statusPublished - 2006

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