A protoporphyrin IX amphiphile bearing hydrophobic-hydrophilic functional regions was synthesised by coupling protoporphyrin IX with methoxytriethylene glycol using (3-(dimethylamino)propyl)ethyl carbodiimide hydrochloride/1-hydroxybenzotriazole followed by a double-cross metathesis with 1-undecene using second-generation Grubb s catalyst. The self-assembling behaviour of the amphiphile in varying concentration of CHCl3/MeOH was investigated, with well-defined nanostructures described as worm-like fibrils and particular aggregates being formed in 1:1 and 1:9 v/v of MeOH/CHCl3, respectively.
Bhosale, S., Kalyankar, M., Bhosale, S., Patil, S., Lalander, C., Langford, S., & Nalage, S. (2011). Supramolecular self-assembly of protoporphyrin IX amphiphiles into worm-like and particular aggregates. Supramolecular Chemistry, 23(3-4), 263 - 268. https://doi.org/10.1080/10610278.2010.523115