Supramolecular protein cages constructed from a crystalline protein matrix

Hashiru Negishi, Satoshi Abe, Keitaro Yamashita, Kunio Hirata, Kento Niwase, Marion Boudes, Fasséli Coulibaly, Hajime Mori, Takafumi Ueno

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)


Protein crystals are formed via ordered arrangements of proteins, which assemble to form supramolecular structures. Here, we show a method for the assembly of supramolecular protein cages within a crystalline environment. The cages are stabilized by covalent cross-linking allowing their release via dissolution of the crystal. The high stability of the desiccated protein crystals allows cages to be constructed.

Original languageEnglish
Pages (from-to)1988-1991
Number of pages4
JournalChemical Communications
Issue number16
Publication statusPublished - 1 Jan 2018

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