@inbook{1da880474c98444fa9375d61c39efddc,
title = "Sulfur Fluoride Exchange (SuFEx)",
abstract = "Sulfur Fluoride Exchange (SuFEx) click chemistry is a new generation technology for creating stable molecular connections with absolute reliability under metal-free conditions. SuFEx builds upon the fundamental principles of click chemistry by exploiting a unique blend of stability and latent reactivity of high oxidation state sulfur fluoride [e.g., S(VI)] functionalities to forge stable covalent linkages at connective SuFEx hubs. In this review, we focus mainly on the SuFEx hubs, sulfuryl fluoride (SO2F2), thionyl tetrafluoride (SOF4), ethenesulfonyl fluoride (ESF), 1-bromoethene-1-sulfonyl fluoride (BESF) and, 2-substituted alkyne-1-sulfonyl fluorides (SASFs). We describe each connector's unique reactivity and their application to SuFEx click chemistry.",
keywords = "1-bromoethene-1-sulfonyl fluoride, 2-substituted alkyne-1-sulfonyl fluorides, click chemistry, connective hubs, diversity-oriented click reactions, ethenesulfonyl fluoride, sulfur fluoride exchange (SuFEx), sulfur fluorides, sulfuryl fluoride, thionyl tetrafluoride",
author = "Giel, {M. C.} and Smedley, {C. J.} and Moses, {J. E.}",
note = "Publisher Copyright: {\textcopyright} 2022 Georg Thieme Verlag. All rights reserved.",
year = "2022",
doi = "10.1055/sos-SD-235-00230",
language = "English",
isbn = "9783132435568",
series = "Science of Synthesis",
publisher = "Georg Thieme",
number = "4",
pages = "435--484",
editor = "Rutjes, {Floris P J T}",
booktitle = "Click Chemistry",
address = "Germany",
edition = "1st",
}