Sulcal curve extraction using Laplace Beltrami eigenfunction level sets

Rosita Shishegar, Mary Tolcos, David W. Walker, Leigh A. Johnston

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

3 Citations (Scopus)

Abstract

The complexity of the human cortex is demonstrated in the intricate pattern of gyri and sulci that arise from the cortical folding process during development. Quantitative assessment of cortical folding is important in the definition of normal brain development and provides insight into neurodevelopmental disorders. In this work, a method for sulcal curve extraction is proposed that combines the advantages of previously proposed depth based and curvature based methods. The technique, derived from Laplace Beltrami eigenfunction level sets, maps mean curvature on the level sets, and incorporates depth information using extracted sulci and gyri, a characteristic previously attributed only to depth based methods. The use of Laplace Beltrami eigenfunction level sets requires neither definition of an outer hull surface nor correspondence between the cortical surface and outer hull, both of which are required by depth based methods. The utility of the method for extracting sulcal curves is demonstrated by application to fetal sheep brain MRI data, imaged at key time points during development.

Original languageEnglish
Title of host publication2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2016)
EditorsJose Principe, Jose Carmena, Justin Sanchez
Place of PublicationPiscataway NJ USA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages4043-4046
Number of pages4
ISBN (Electronic)9781457702204
ISBN (Print)9781457702198
DOIs
Publication statusPublished - 2016
EventInternational Conference of the IEEE Engineering in Medicine and Biology Society 2016 - Walt Disney World Resort, Orlando, United States of America
Duration: 16 Aug 201620 Aug 2016
Conference number: 38th
https://embc.embs.org/2016/
https://ieeexplore.ieee.org/xpl/conhome/7580725/proceeding (Proceedings)

Conference

ConferenceInternational Conference of the IEEE Engineering in Medicine and Biology Society 2016
Abbreviated titleEMBC 2016
Country/TerritoryUnited States of America
CityOrlando
Period16/08/1620/08/16
Internet address

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