Substance Misuse: Heroin

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Heroin is one of the more common illicit drugs used around the world, often in combination with other drugs that depress the central nervous system. Repeated use of heroin leads to a dependence and tolerance requiring higher doses to achieve the desired pharmacological effect. The risk of sudden death is high, particularly if used with other drugs. Blood concentrations of the active metabolite morphine is poorly correlated with toxicity. Repeated use of heroin can lead to significant ill-health and injury, and sudden death.

Original languageEnglish
Title of host publicationEncyclopedia of Forensic and Legal Medicine
PublisherAcademic Press
Number of pages6
ISBN (Electronic)9780128000557
ISBN (Print)9780128000342
Publication statusPublished - 2016


  • Buprenorphine
  • Central nervous system depression
  • Dependence
  • Diacetylmorphine
  • Heroin
  • Methadone
  • Mortality
  • Narcotic
  • Opiate
  • Opioid
  • Opium
  • Respiration
  • Tolerance
  • Toxicity

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