Studies towards a concise enantioselective synthesis of roseophilins

Daniel J Kerr, Bernard L Flynn

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5 Citations (Scopus)

Abstract

An oxazolidone auxiliary-controlled asymmetric Nazarov reaction has been applied to the synthesis of the cyclopentyl-fused pyrrole core of roseophilins. Additionally, a concise synthetic route to the pyrrole-furan biaryl fragment required in the synthesis of the recently isolated dechlororoseophilin is described. It is anticipated that these two syntheses can be combined in future efforts to provide efficient, convergent access to (+)-dechlororoseophilin.
Original languageEnglish
Pages (from-to)1821-1828
Number of pages8
JournalAustralian Journal of Chemistry
Volume68
Issue number12
DOIs
Publication statusPublished - 2015

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