Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

Ossama El-Kabbani; Vincenzo Carbone; Connie Darmanin; Mitsuru Oka; Andre Mitschler; Alberto D Podjarny; Clemens Schulze-Briese; Roland Poh-Tuck Chung

doi:10.1021/jm050412o

Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

Ossama El-Kabbani, Vincenzo Carbone, Connie Darmanin, Mitsuru Oka, Andre Mitschler, Alberto D Podjarny, Clemens Schulze-Briese, Roland Poh-Tuck Chung

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

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Abstract

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Original language	English
Pages (from-to)	5536 - 5542
Number of pages	7
Journal	Journal of Medicinal Chemistry
Volume	48
Issue number	17
DOIs	https://doi.org/10.1021/jm050412o
Publication status	Published - 2005

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El-Kabbani, O., Carbone, V., Darmanin, C., Oka, M., Mitschler, A., Podjarny, A. D., Schulze-Briese, C., & Chung, R. P-T. (2005). Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. Journal of Medicinal Chemistry, 48(17), 5536 - 5542. https://doi.org/10.1021/jm050412o

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author = "Ossama El-Kabbani and Vincenzo Carbone and Connie Darmanin and Mitsuru Oka and Andre Mitschler and Podjarny, {Alberto D} and Clemens Schulze-Briese and Chung, {Roland Poh-Tuck}",

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El-Kabbani, O, Carbone, V, Darmanin, C, Oka, M, Mitschler, A, Podjarny, AD, Schulze-Briese, C & Chung, RP-T 2005, 'Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity', Journal of Medicinal Chemistry, vol. 48, no. 17, pp. 5536 - 5542. https://doi.org/10.1021/jm050412o

Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity. / El-Kabbani, Ossama; Carbone, Vincenzo; Darmanin, Connie et al.
In: Journal of Medicinal Chemistry, Vol. 48, No. 17, 2005, p. 5536 - 5542.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

AU - El-Kabbani, Ossama

AU - Carbone, Vincenzo

AU - Darmanin, Connie

AU - Oka, Mitsuru

AU - Mitschler, Andre

AU - Podjarny, Alberto D

AU - Schulze-Briese, Clemens

AU - Chung, Roland Poh-Tuck

PY - 2005

Y1 - 2005

N2 - Photocopy or off print of article

AB - Photocopy or off print of article

UR - http://pubs.acs.org/journals/jmcmar/

U2 - 10.1021/jm050412o

DO - 10.1021/jm050412o

M3 - Article

SN - 0022-2623

VL - 48

SP - 5536

EP - 5542

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 17

ER -

Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity

Abstract

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