Structure description and identification using the tableau representation of protein folding patterns

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    Abstract

    We have developed a concise tableau representation of protein folding patterns, based on the order and contact patterns of elements of secondary structure: helices and strands of sheet. The tableaux provide a database, derived from the protein data bank, minable for studies on the general principles of protein architecture, including investigation of the relationship between local supersecondary structure of proteins and the complete folding topology. This chapter outlines the tableaux representation of protein folding patterns and methods to use them to identify structural and substructural similarities.
    Original languageEnglish
    Title of host publicationProtein Supersecondary Structures
    EditorsAlexander E Kister
    Place of PublicationNew York NY USA
    PublisherHumana Press
    Pages51 - 59
    Number of pages9
    ISBN (Electronic)9781627030656
    ISBN (Print)9781627030649
    DOIs
    Publication statusPublished - 2013

    Publication series

    NameMethods in Molecular Biology
    PublisherHumana Press, Inc.
    ISSN (Print)1064-3745
    ISSN (Electronic)1940-6029

    Keywords

    • Protein folding pattern
    • Substructure search
    • Supersecondary structure
    • Tableau representation

    Cite this

    Konagurthu, A. S., & Lesk, A. M. (2013). Structure description and identification using the tableau representation of protein folding patterns. In A. E. Kister (Ed.), Protein Supersecondary Structures (pp. 51 - 59). (Methods in Molecular Biology). Humana Press. https://doi.org/10.1007/978-1-62703-065-6_4