Structure-based optimization and biological evaluation of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors

Ossama El-Kabbani; Peter John Scammells; Tom Day; Urmi Dhagat; Satoshi Endo; Toshiyuki Matsunaga; Midori Soda; Akira Hara

doi:10.1016/j.ejmech.2010.08.052

Structure-based optimization and biological evaluation of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors

Ossama El-Kabbani, Peter John Scammells, Tom Day, Urmi Dhagat, Satoshi Endo, Toshiyuki Matsunaga, Midori Soda, Akira Hara

Medicinal Chemistry

Research output: Contribution to journal › Article › Research › peer-review

18 Citations (Scopus)

Original language	English
Pages (from-to)	5309 - 5317
Number of pages	9
Journal	European Journal of Medicinal Chemistry
Volume	45
Issue number	11
DOIs	https://doi.org/10.1016/j.ejmech.2010.08.052
Publication status	Published - 2010

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10.1016/j.ejmech.2010.08.052

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title = "Structure-based optimization and biological evaluation of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors",

author = "Ossama El-Kabbani and Scammells, {Peter John} and Tom Day and Urmi Dhagat and Satoshi Endo and Toshiyuki Matsunaga and Midori Soda and Akira Hara",

year = "2010",

doi = "10.1016/j.ejmech.2010.08.052",

language = "English",

volume = "45",

pages = "5309 -- 5317",

journal = "European Journal of Medicinal Chemistry",

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T1 - Structure-based optimization and biological evaluation of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors

AU - El-Kabbani, Ossama

AU - Scammells, Peter John

AU - Day, Tom

AU - Dhagat, Urmi

AU - Endo, Satoshi

AU - Matsunaga, Toshiyuki

AU - Soda, Midori

AU - Hara, Akira

PY - 2010

Y1 - 2010

UR - http://www.sciencedirect.com/science/article/pii/S0223523410006331

U2 - 10.1016/j.ejmech.2010.08.052

DO - 10.1016/j.ejmech.2010.08.052

M3 - Article

SN - 0223-5234

VL - 45

SP - 5309

EP - 5317

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

IS - 11

ER -

Structure-based optimization and biological evaluation of human 20alpha-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors

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