TY - CHAP
T1 - Structural glycobiology of antibody recognition in xenotransplantation and cancer immunotherapy
AU - Agostino, Mark James
AU - Farrugia, William
AU - Sandrin, Mauro Sergio
AU - Scott, Andrew M
AU - Yuriev, Elizabeth
AU - Ramsland, Paul Allen
PY - 2012
Y1 - 2012
N2 - In this chapter, we discuss the structural glycobiology of the key antibody?carbohydrate interactions important in xenotransplantation and cancer immunotherapy. Progress in both fields is reliant on further mechanistic knowledge of the underlying complex biosynthetic pathways and the structural basis for antibody recognition of isolated and cellular forms of the target carbohydrates.
AB - In this chapter, we discuss the structural glycobiology of the key antibody?carbohydrate interactions important in xenotransplantation and cancer immunotherapy. Progress in both fields is reliant on further mechanistic knowledge of the underlying complex biosynthetic pathways and the structural basis for antibody recognition of isolated and cellular forms of the target carbohydrates.
UR - http://download.springer.com/static/pdf/198/chp%253A10.1007%252F978-3-7091-0870-3_9.pdf?auth66=1364441781_451755a87e862b1c602f92329f66a743&ext=.pdf
U2 - 10.1007/978-3-7091-0870-3_9
DO - 10.1007/978-3-7091-0870-3_9
M3 - Chapter (Book)
SN - 9783709108697
SP - 203
EP - 228
BT - Anticarbohydrate antibodies
A2 - Kosma, Paul
A2 - Muller-Loennies, Sven
PB - Springer
CY - New York USA
ER -
