TY - JOUR
T1 - Structural biology: Torqueing about pores
AU - Whisstock, James
AU - Dunstone, Michelle Anne
PY - 2013
Y1 - 2013
N2 - Cryo-EM, crystallography, biochemical experiments and computational approaches have been used to study different intermediate states of the Aeromonas hydrophila toxin aerolysin en route to pore formation. These results reveal that an unexpected and marked rotation of the core aerolysin machinery is required to unleash the membrane-spanning regions.
AB - Cryo-EM, crystallography, biochemical experiments and computational approaches have been used to study different intermediate states of the Aeromonas hydrophila toxin aerolysin en route to pore formation. These results reveal that an unexpected and marked rotation of the core aerolysin machinery is required to unleash the membrane-spanning regions.
UR - http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=24045807
U2 - 10.1038/nchembio.1341
DO - 10.1038/nchembio.1341
M3 - Article
VL - 9
SP - 605
EP - 606
JO - Nature Chemical Biology
JF - Nature Chemical Biology
SN - 1552-4450
IS - 10
ER -