Structural biology in plant natural product biosynthesis - Architecture of enzymes from monoterpenoid indole and tropane alkaloid biosynthesis

Joachim Stöckigt, Santosh Panjikar

Research output: Contribution to journalReview ArticleResearchpeer-review

39 Citations (Scopus)

Abstract

Several cDNAs of enzymes catalyzing biosynthetic pathways of plant-derived alkaloids have recently been heterologously expressed, and the production of appropriate enzymes from ajmaline and tropane alkaloid biosynthesis in bacteria allows their crystallization. This review describes the architecture of these enzymes with and without their ligands.

Original languageEnglish
Pages (from-to)1382-1400
Number of pages19
JournalNatural Product Reports
Volume24
Issue number6
DOIs
Publication statusPublished - 2007
Externally publishedYes

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