Structural analysis of the PTEN:P-Rex2 signaling complex reveals how cancer-associated mutations coordinate to hyperactivate Rac1

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  Structural characterisation of the co-inhibitory complex formed by the tumour suppressor PTEN and the metastatic factor PREX2

  Ellisdon, A. (Primary Chief Investigator (PCI)), Elmlund, H. (Chief Investigator (CI)) & Halls, M. (Chief Investigator (CI))

  1/01/18 → 31/12/20

  Project: Research

• Structural and functional characterisation of the oncogene P-Rex1

  Ellisdon, A. (Primary Chief Investigator (PCI)), Whisstock, J. (Chief Investigator (CI)), Elmlund, H. (Chief Investigator (CI)) & Halls, M. (Chief Investigator (CI))

  1/01/17 → 31/12/19

  Project: Research

• Characterisation of a novel oncogene in breast cancer

  Mitchell, C., Ellisdon, A. & McLean, C.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/16 → 31/12/21

  Project: Research

• ARC Centre of Excellence in Advanced Molecular Imaging

  Whisstock, J. (Primary Chief Investigator (PCI)), Abbey, B. (Chief Investigator (CI)), Nugent, K. (Chief Investigator (CI)), Quiney, H. M. (Chief Investigator (CI)), Godfrey, D. I. (Chief Investigator (CI)), Heath, W. (Chief Investigator (CI)), Fairlie, D. P. (Chief Investigator (CI)), Chapman, H. (Partner Investigator (PI)), Peele, A. (Partner Investigator (PI)), Davey, J. (Partner Investigator (PI)) & Wittmann, A. (Project Manager)

  30/06/14 → 31/03/21

  Project: Research

• Signalosomes and compartmentalisation in cellular homeostasis and disease

  Halls, M. (Primary Chief Investigator (PCI))

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/14 → 31/10/19

  Project: Research