Stress-related impairments in cellular immunity

Ronald Glacer, Janice K. Kiecolt-Glacer, Julie C. Stout, Kathleen L. Tarr, Carl E. Speicher, Jane E. Holliday

Research output: Contribution to journalArticleResearchpeer-review

138 Citations (Scopus)

Abstract

The percentages of total T-lymphocytes (OKT-3+), helper T-cells (OKT-4+), and suppressor T-cells (OKT-8+) were significantly lower in blood samples obtained from 40 medical students during examinations, compared to baseline values obtained 6 weeks earlier. In addition, the response of T-lymphocytes to stinulation by phytotemagglutinin and concanavillin A was also significantly lower during examinations, compared to baseline. Self-report data documented significantly greater distress associated with examinations. The data have implications for immunosuppressive disorders and stress-related illness.

Original languageEnglish
Pages (from-to)233-239
Number of pages7
JournalPsychiatry Research
Volume16
Issue number3
DOIs
Publication statusPublished - 1 Jan 1985

Keywords

  • blastogenesis
  • helper cells
  • Stress-related impairment
  • suppressor cells

Cite this