Abstract
Chronic stress drives cancer progression, but the routes of metastasis are unclear. We recently demonstrated that chronic stress activates a neural-inflammatory signaling axis to remodel lymphatic vasculature and increase lymph flow. This unanticipated crosstalk between stress and the lymphatic system provides pathways of tumor cell dissemination and accelerates metastasis.
Original language | English |
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Article number | e1177674 |
Number of pages | 3 |
Journal | Molecular & Cellular Oncology |
Volume | 3 |
Issue number | 4 |
DOIs | |
Publication status | Published - 3 Jul 2016 |
Keywords
- Adrenergic
- lymphatic
- metastasis
- sympathetic nervous system
- β-blocker