Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation

S. V. Dobatkin; E. A. Lukyanova; N. S. Martynenko; N. Yu Anisimova; M. V. Kiselevskiy; M. V. Gorshenkov; N. Yu Yurchenko; George I. Raab; V. S. Yusupov; N. Birbilis; G. A. Salishchev; Y. Z. Estrin

doi:10.1088/1757-899X/194/1/012004

Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation

S. V. Dobatkin, E. A. Lukyanova, N. S. Martynenko, N. Yu Anisimova, M. V. Kiselevskiy, M. V. Gorshenkov, N. Yu Yurchenko, George I. Raab, V. S. Yusupov, N. Birbilis, G. A. Salishchev, Y. Z. Estrin

Materials Science & Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

40 Citations (Scopus)

Abstract

The effect of severe plastic deformation on the structure, mechanical properties, corrosion resistance, and biocompatibility of the WE43 (Mg-Y-Nd-Zr) alloy earmarked for applications as bioresorbable material has been studied. The alloy was deformed by rotary swaging (RS), equal channel angular pressing (ECAP), and multiaxial deformation (MAD). The microstructure examination by transmission electron microscopy showed that all SPD modes lead to the formation of ultrafine-grained structure with a structural element size of 0.5-1 μm and the Mg₁₂Nd phase particles 0.3 μm in size. The microstructure refinement by all three treatments resulted in strengthening of the alloy. ECAP and MAD also raised ductility to up to 12-17%, while RS increased the ultimate tensile strength to up to 415 MPa. The study of the corrosion properties showed that SPD does not affect the electrochemical corrosion of the alloy. Its biocompatibility in vitro was estimated after incubation of the samples with red blood cells (hemolysis study), white blood cells (cell viability assay), and mesenchymal stromal cells (cell proliferation analysis). The biodegradation rate in fetal bovine serum was also evaluated. ECAP and MAD were found to cause some deceleration of biodegradation by slowing down the gas formation in the biological fluid and, compared to MSC, to improve the biocompatibility of the WE43 alloy.

Original language	English
Title of host publication	7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017
Place of Publication	Bristol UK
Publisher	IOP Publishing
Number of pages	8
DOIs	https://doi.org/10.1088/1757-899X/194/1/012004
Publication status	Published - 8 May 2017
Event	International Conference on Nanomaterials by Severe Plastic Deformation 2017 - Sydney, Australia Duration: 2 Jul 2017 → 7 Jul 2017 Conference number: 7th http://www.nanospd7.com/

Publication series

Name	IOP Conference Series: Materials Science and Engineering
Publisher	IOP Publishing
Number	1
Volume	194
ISSN (Print)	1757-8981

Conference

Conference	International Conference on Nanomaterials by Severe Plastic Deformation 2017
Abbreviated title	NanoSPD7 2017
Country/Territory	Australia
City	Sydney
Period	2/07/17 → 7/07/17
Internet address	http://www.nanospd7.com/

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Dobatkin, S. V., Lukyanova, E. A., Martynenko, N. S., Anisimova, N. Y., Kiselevskiy, M. V., Gorshenkov, M. V., Yurchenko, N. Y., Raab, G. I., Yusupov, V. S., Birbilis, N., Salishchev, G. A., & Estrin, Y. Z. (2017). Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation. In 7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017 (IOP Conference Series: Materials Science and Engineering; Vol. 194, No. 1). IOP Publishing. https://doi.org/10.1088/1757-899X/194/1/012004

Dobatkin, S. V. ; Lukyanova, E. A. ; Martynenko, N. S. et al. / Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation. 7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017. Bristol UK : IOP Publishing, 2017. (IOP Conference Series: Materials Science and Engineering; 1).

@inproceedings{38bc1930709841ea87f3704092c959fd,

title = "Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation",

abstract = "The effect of severe plastic deformation on the structure, mechanical properties, corrosion resistance, and biocompatibility of the WE43 (Mg-Y-Nd-Zr) alloy earmarked for applications as bioresorbable material has been studied. The alloy was deformed by rotary swaging (RS), equal channel angular pressing (ECAP), and multiaxial deformation (MAD). The microstructure examination by transmission electron microscopy showed that all SPD modes lead to the formation of ultrafine-grained structure with a structural element size of 0.5-1 μm and the Mg12Nd phase particles 0.3 μm in size. The microstructure refinement by all three treatments resulted in strengthening of the alloy. ECAP and MAD also raised ductility to up to 12-17%, while RS increased the ultimate tensile strength to up to 415 MPa. The study of the corrosion properties showed that SPD does not affect the electrochemical corrosion of the alloy. Its biocompatibility in vitro was estimated after incubation of the samples with red blood cells (hemolysis study), white blood cells (cell viability assay), and mesenchymal stromal cells (cell proliferation analysis). The biodegradation rate in fetal bovine serum was also evaluated. ECAP and MAD were found to cause some deceleration of biodegradation by slowing down the gas formation in the biological fluid and, compared to MSC, to improve the biocompatibility of the WE43 alloy.",

author = "Dobatkin, {S. V.} and Lukyanova, {E. A.} and Martynenko, {N. S.} and Anisimova, {N. Yu} and Kiselevskiy, {M. V.} and Gorshenkov, {M. V.} and Yurchenko, {N. Yu} and Raab, {George I.} and Yusupov, {V. S.} and N. Birbilis and Salishchev, {G. A.} and Estrin, {Y. Z.}",

year = "2017",

month = may,

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doi = "10.1088/1757-899X/194/1/012004",

language = "English",

series = "IOP Conference Series: Materials Science and Engineering",

publisher = "IOP Publishing",

number = "1",

booktitle = "7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017",

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note = "International Conference on Nanomaterials by Severe Plastic Deformation 2017, NanoSPD7 2017 ; Conference date: 02-07-2017 Through 07-07-2017",

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Dobatkin, SV, Lukyanova, EA, Martynenko, NS, Anisimova, NY, Kiselevskiy, MV, Gorshenkov, MV, Yurchenko, NY, Raab, GI, Yusupov, VS, Birbilis, N, Salishchev, GA & Estrin, YZ 2017, Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation. in 7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017. IOP Conference Series: Materials Science and Engineering, no. 1, vol. 194, IOP Publishing, Bristol UK, International Conference on Nanomaterials by Severe Plastic Deformation 2017, Sydney, New South Wales, Australia, 2/07/17. https://doi.org/10.1088/1757-899X/194/1/012004

Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation. / Dobatkin, S. V.; Lukyanova, E. A.; Martynenko, N. S. et al.

7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017. Bristol UK : IOP Publishing, 2017. (IOP Conference Series: Materials Science and Engineering; Vol. 194, No. 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Research › peer-review

TY - GEN

T1 - Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation

AU - Dobatkin, S. V.

AU - Lukyanova, E. A.

AU - Martynenko, N. S.

AU - Anisimova, N. Yu

AU - Kiselevskiy, M. V.

AU - Gorshenkov, M. V.

AU - Yurchenko, N. Yu

AU - Raab, George I.

AU - Yusupov, V. S.

AU - Birbilis, N.

AU - Salishchev, G. A.

AU - Estrin, Y. Z.

N1 - Conference code: 7th

PY - 2017/5/8

Y1 - 2017/5/8

N2 - The effect of severe plastic deformation on the structure, mechanical properties, corrosion resistance, and biocompatibility of the WE43 (Mg-Y-Nd-Zr) alloy earmarked for applications as bioresorbable material has been studied. The alloy was deformed by rotary swaging (RS), equal channel angular pressing (ECAP), and multiaxial deformation (MAD). The microstructure examination by transmission electron microscopy showed that all SPD modes lead to the formation of ultrafine-grained structure with a structural element size of 0.5-1 μm and the Mg12Nd phase particles 0.3 μm in size. The microstructure refinement by all three treatments resulted in strengthening of the alloy. ECAP and MAD also raised ductility to up to 12-17%, while RS increased the ultimate tensile strength to up to 415 MPa. The study of the corrosion properties showed that SPD does not affect the electrochemical corrosion of the alloy. Its biocompatibility in vitro was estimated after incubation of the samples with red blood cells (hemolysis study), white blood cells (cell viability assay), and mesenchymal stromal cells (cell proliferation analysis). The biodegradation rate in fetal bovine serum was also evaluated. ECAP and MAD were found to cause some deceleration of biodegradation by slowing down the gas formation in the biological fluid and, compared to MSC, to improve the biocompatibility of the WE43 alloy.

AB - The effect of severe plastic deformation on the structure, mechanical properties, corrosion resistance, and biocompatibility of the WE43 (Mg-Y-Nd-Zr) alloy earmarked for applications as bioresorbable material has been studied. The alloy was deformed by rotary swaging (RS), equal channel angular pressing (ECAP), and multiaxial deformation (MAD). The microstructure examination by transmission electron microscopy showed that all SPD modes lead to the formation of ultrafine-grained structure with a structural element size of 0.5-1 μm and the Mg12Nd phase particles 0.3 μm in size. The microstructure refinement by all three treatments resulted in strengthening of the alloy. ECAP and MAD also raised ductility to up to 12-17%, while RS increased the ultimate tensile strength to up to 415 MPa. The study of the corrosion properties showed that SPD does not affect the electrochemical corrosion of the alloy. Its biocompatibility in vitro was estimated after incubation of the samples with red blood cells (hemolysis study), white blood cells (cell viability assay), and mesenchymal stromal cells (cell proliferation analysis). The biodegradation rate in fetal bovine serum was also evaluated. ECAP and MAD were found to cause some deceleration of biodegradation by slowing down the gas formation in the biological fluid and, compared to MSC, to improve the biocompatibility of the WE43 alloy.

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U2 - 10.1088/1757-899X/194/1/012004

DO - 10.1088/1757-899X/194/1/012004

M3 - Conference Paper

AN - SCOPUS:85019726798

T3 - IOP Conference Series: Materials Science and Engineering

BT - 7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017

PB - IOP Publishing

CY - Bristol UK

T2 - International Conference on Nanomaterials by Severe Plastic Deformation 2017

Y2 - 2 July 2017 through 7 July 2017

ER -

Dobatkin SV, Lukyanova EA, Martynenko NS, Anisimova NY, Kiselevskiy MV, Gorshenkov MV et al. Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation. In 7th International Conference on Nanomaterials by Severe Plastic Deformation, NanoSPD 2017. Bristol UK: IOP Publishing. 2017. (IOP Conference Series: Materials Science and Engineering; 1). https://doi.org/10.1088/1757-899X/194/1/012004

Strength, corrosion resistance, and biocompatibility of ultrafine-grained Mg alloys after different modes of severe plastic deformation

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