Projects per year
Abstract
Specific clinical applications of RNA interference (RNAi) can benefit from a concurrent activation of the immune system. This is the case for small interfering RNAs (siRNAs) with antitumor or antiviral activities. This chapter provides a brief overview of the strategies reported to date to design siRNAs with gene silencing and immune activating properties, as well as methods for the validation of immunostimulatory activities.
Original language | English |
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Title of host publication | siRNA Design |
Subtitle of host publication | Methods and Protocols |
Editors | Debra J. Taxman |
Place of Publication | Totowa, NJ USA |
Publisher | Humana Press |
Chapter | 10 |
Pages | 179-191 |
Number of pages | 13 |
Edition | 1st |
ISBN (Print) | 9781627031189 |
DOIs | |
Publication status | Published - 2013 |
Publication series
Name | Methods in Molecular Biology |
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Publisher | Humana Press |
Volume | 942 |
ISSN (Print) | 1064-3745 |
ISSN (Electronic) | 1940-6029 |
Projects
- 2 Finished
-
microRNA regulation of antiviral responses
Gantier, M. (Primary Chief Investigator (PCI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/12 → 31/12/14
Project: Research
-
Protein recognition of small RNAs in innate immunity
Williams, B. (Primary Chief Investigator (PCI)), Wilce, M. (Chief Investigator (CI)) & Wilce, J. (Chief Investigator (CI))
NHMRC - National Health and Medical Research Council (Australia)
1/01/11 → 31/12/13
Project: Research