Abstract
β-Amino ketones are of increasing interest owing to their utility as important synthetic precursors in the synthesis of bioactive molecules and natural products. As a result numerous syntheses of β-amino ketones have emerged in recent years. Of particular significance are those methods that allow access to stereopure β-amino ketones. This review highlights recent advances in stereoselective syntheses of β-amino ketones and also illustrates the importance of β-amino ketones as useful synthons.
Original language | English |
---|---|
Pages (from-to) | 260-289 |
Number of pages | 30 |
Journal | Current Organic Chemistry |
Volume | 18 |
Issue number | 2 |
DOIs | |
Publication status | Published - 2014 |
Externally published | Yes |
Keywords
- β-amino ketones
- Amino alcohols
- Conjugate additions
- Diastereoselectivity
- Enantioselectivity
- Mannich addition